I found today that you can run the Microsoft Malicious Software Removal tool interactively, by running “mrt” from the command line. I found this from Mark Minasi’s (http://www.minasi.com/) newsletter. I have heard both Mark Minasi and his associate Rhonda Layfield speak at CITPG meetings. Both are quite knowledgeable and engaging speakers. Mark, like many IT professionals, tends to wear his self-appointed expertise as a mantle. Rhonda has no sharp edges, and is no way second string.
If you get a chance to hear either of them speak, it is worth the time.